Development of an HTRF method to determine the stoichiometry of subunits...
MAb Anti cmyc-XL665 HTRF®
- High affinity
MAb Anti cmyc-XL665 is an IgG1 raised against a synthetic peptide corresponding to the 408-439 sequence of human c-myc protein labeled with XL. It recognizes the EQKLISEEDL motif and is specific for human c-myc, although a slight cross-reaction has been observed with murine c-myc at high antibody concentration.
This reagent can be used in both biochemical and cellular formats to study a wide variety of interactions: protein/protein, protein/peptide, protein/DNA, receptor/ligand.
HTRF can detect a broad range of affinity constants ranging from picomolar to low millimolar.
- LARGE COMPLEXES DETECTION
- BATCH-TO-BATCH REPRODUCIBILITY
- LOW TO HIGH KD DETECTION
|Motif/Species||Antibody||Active Moiety/5,000 tests||Species and Subtype||Specificity|
|cMYC||MAb 9E10||5-10 µg||Mouse IgG1||EQKLISEEDL peptide|
In collaboration with Bristol Myers Squibb - Scientific Presentations
In collaboration with Scripps - Scientific Presentations
In collaboration with Sanford/Burnham - Scientific Presentations
Benefits and considerations of HTRF - Scientific Presentations
In collaboration with Lead Discovery Center GmbH - Scientific Presentations
In collaboration with MRC - Scientific Presentations
Benefit from unlimited flexibility for your assay development - Flyers
In collaboration with Boehringer Ingelheim - Posters
Every interaction is within range - Technical Notes
61MYCXLF-61MYCXLA-61MYCXLB - Product Insert
Easy pharmacological characterization of PPI modulators. - Technical Notes
Deciphering low- and high affinity interactions - Application Notes
Monitoring nuclear receptor binding with HTRF assays - Application Notes
Challenge large complexes with HTRF assays - Application Notes
Get the brochure about technology comparison. - Brochures
See how peer researchers challenge the viral life cycle with PPI assays - Application Notes
Plate Reader Requirement
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Binding between subunits within an oligomeric cell surface receptor can ...
Evaluation of the "druggability" potential of 1664 compounds using HTRF...